 |
Antibiotics are rejected in the environment after their use for treating human and animal bacterial infections. These residues are poorly eliminated by the actual wastewater treatment processes, impacting both animal, human and environmental health. This led to the emergence of antibiotic resistance in bacterial pathogens. To fight this issue, the last decades have been marked by the apparition of photopharmacology. This approach based on the use of the light is a promising way to control the antibiotic activity of a drug. Indeed, under a UV light irradiation, the drug is activated and exercises its antibacterial activity. In contrary, when the drug is released in the environment, its visible light illumination enables its deactivation. Thus, this work proposes the design of antibacterial molecules to be used for photopharmacology to treat bacterial infections.
